The basic evidence based research steps are:
- Begin with a problem or issue stated as a question. 1 2
- Plan your search for the levels of evidence you need. 3
- Search for secondary or primary sources and primary evidence. 4 5
- Evaluate your results. 6 7
- Implement your findings. 8 9
- Publish your findings to build the evidence base. 10
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Reporting meta-analyses of observational studies (11)
Checklist for authors, editors, and reviewers of meta-analyses of observational studies
Reporting of background should include:
- Problem definition
- Hypothesis statement
- Description of study outcome(s)
- Type of exposure or intervention used
- Type of study designs
- Study population
Reporting of search strategy should include:
- Qualifications of searchers (eg, librarians and investigators)
- Search strategy, including time period included in the synthesis and keywords
- Effort to include all available studies, including contact with authors
- Databases and registries searched
- Search software use, name and version, including special features used (eg, explosion)
- Use of hand searching (eg, reference lists of obtained articles)
- List of citations located and those excluded, including justification
- Method of addressing articles published in languages other than English
- Method of handling abstracts and unpublished studies
- Description of any contact with authors
Reporting of methods should include:
- Description of relevance or appropriateness of studies assembled for assessing the hypothesis to be tested
- Rationale for the selection and coding of date (eg, sound clinical principles or convenience)
- Documentation of how data were classified and coded (eg, multiple raters, blinding, and interrater reliability)
- Assessment of confounding (eg, comparability of cases and controls in studies where appropriate)
- Assessment of study quality, including blinding of quality assessors; stratification or regression on possible predictors of study results
- Assessment of heterogeneity
- Description of statistical methods (eg, complete description of fixed or random effects models, justification of whether the chosen models account for predictors of study results, dose-response models, or cumulative meta-analysis ) in sufficient detail to be replicated
Reporting of results should include:
- Graphic summarizing individual study estimates an overall estimate
- Table giving descriptive information for each study included
- Results of sensitivity testing (eg, subgroup analysis)
- Indication of statistical uncertainty of findings
Reporting of discussion should include:
- Quantitative assessment of bias (eg, exclusion of non-English-language citations)
- Assessment of quality of included studies
Reporting of conclusions should include:
- Consideration of alternative explanations for observed results
- Generalization of the conclusions (ie, appropriate for the data presented and within the domain of the literature review)
- Guidelines for future research
- Disclosure of funding source
Links to help you prepare your publication or presentation:
Nurse Author & Editor Newsletter http://www.nurseauthoreditor.com/forauthors.asp
CEBM Presentation Prescription www.cebm.net/index.aspx?o=1530
CONSORT: transparent reporting of trials www.consort-statement.org
BMJ http://resources.bmj.com/bmj/about-bmj/evidence-based-publishing
Other "Reporting of research checklists" National Center for the Dissemination of Disability Research - KT Library www.ncddr.org/ktinfocenter/checklists.html
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